Putting the immune system in control
DCprime is the front-runner in the field of relapse vaccines, a new class of oncology vaccines administered after standard of care therapy to delay or prevent disease recurrence. Relapse vaccines are aimed at improving survival by putting the patient’s immune system back in control while tumor burden is low, and the immune system is in relatively good shape.
A growing pipeline of relapse vaccines
Our lead product DCP-001 is a cell-based vaccine addressing blood cancers with a high risk of relapse. DCP-001 is currently being evaluated in a Phase II clinical trial in acute myeloid leukemia (AML). We are pursuing similar vaccination approaches in other malignancies, including solid tumors.
- DCprime Receives US FDA Orphan Drug Designation for DCP-001 in Acute Myeloid Leukemia 5 December, 2019 Leiden, The Netherlands, December 05, 2019 –DCprime, the front-runner in the field of relapse vaccines, today announced that the United States Food and Drug Administration (FDA) has granted Orphan Drug Designation to DCP-001 for the treatment of acute myeloid leukemia (AML). DCP-001 is a cell-based vaccine addressing blood cancers with a high risk of relapse … Read more
- DCprime to Present Long-term Follow-up and Survival Data for Lead Relapse Vaccine Candidate DCP-001 in High-Risk AML and MDS Patients 13 November, 2019 Presentation at ASH Annual Meeting Shows Potential to Prolong Relapse-Free Survival and Overall Survival Using an Allogeneic Cell-based Vaccine in the Post-Remission Setting Leiden, The Netherlands, November 13, 2019 –DCprime, the front-runner in the field of relapse vaccines, today announced the presentation of updated clinical results for its lead product DCP-001 at the upcoming 61st Annual … Read more
- DCprime Presents Preclinical Data on Novel Vaccination Concept Using the DCOne® Cell Line in Solid Tumour Models 6 November, 2019 Presentation at SITC Shows Potential to Flag Solid Tumours as a Target for the Immune System to Attack Using the Company’s DCOne® Cell Vaccine Loaded with a Foreign Antigen Leiden, The Netherlands, November 6, 2019 –DCprime, the front-runner in the field of relapse vaccines, today announced the presentation of preclinical proof-of-concept results at the 34th Annual … Read more